Jakarta – BRIN Public Relations. The National Research and Innovation Agency (BRIN) through the funding scheme of Health Innovation Product Testing (PPIK) facilitation will administer clinical trial on a spinal implant prototype. This prototype is the health innovation product produced by the Center for Advanced Materials Research (PRMM) of the Nanotechnology and Materials Research Organization.

This prototype is one of three health innovation products that received funding for clinical trials through the PPIK facilitation scheme. This spinal implant product is expected to be a solution to improve the condition of those having spinal disorder.

Senior Engineer at PRMM, I Nyoman Jujur explained the benefits of spinal implant products which include forming a supporting construction that corrects spinal deformities and instability. “If someone had an accident, usually he/she will have problem in the spine. This product can correct the spinal position,” said I Nyoman in a Webinar on Research and Innovation Funding Facilitation edition of the Health Innovation Product Testing Facilitation, held Tuesday (15/03).

In addition, use of spinal implants is also beneficial for correcting deformities caused by degenerative disc diseases, infection, tumor, and fracture in the spinal area. The use of domestically produced spinal implants will substitute import products and strengthen the domestic technology for medical device production.

I Nyoman shared the journey of spinal implant research that began in 2016. “At the beginning of research, we started by focusing on mastering the materials that would be used for spinal implants,” said I Nyoman.

According to him, the materials needed for this product are of course medical materials with special characteristics. Based on the results of consideration and testing, titanium was finally chosen as the material for manufacturing spinal implants.

“The titanium material is selected through testing to make sure that the material used conforms to the specified standards,” he added.

In 2020, this product had its first preclinical test, with the aim of measuring the performance of the prototype. At this stage of preclinical testing, various problems that require improvement were found.

After correcting the deficiencies found in stage 1 of the preclinical testing, we carried out stage 2 preclinical tests, and so on, until the results conformed to the specified standards. “After confirmation that the spinal implant prototype had conformed to standards and the desire of users and the industry, this product was submitted for clinical trials,” he continued.

At the end of 2021, said I Nyoman, through the PPIK facilitation funding scheme, the prototype of spinal implant was submitted for clinical trials in partnership with PT. Zenith Allmart Precisindo a company engaging in precision metal casting using the investment casting techniques. PT. Zenith Allmart Precisindo will commercialize spinal implant products to the user community.

CEO of PT. Zenith Allmart Precisindo, Allan Chanrawinata said that the collaboration between the industry and researchers is absolutely necessary, considering that conducting research, especially in the health sector, requires many procedures and standards that must be adhered to. “This is the section that researchers at BRIN understand. Therefore, collaboration between BRIN, the industry, and doctors really helps the production process in accordance with the objectives,” said Allan.

According to Allan, the collaboration between various parties in the completion of this product is very useful, as each party can provide a lot of input and information ranging from technical product improvements to information related to the market needs for this health product. “The results of discussion between the three collaborating parties, namely BRIN, the industry, and doctors, will focus on a desired prototype design,” concluded Allan. (pur)