Serpong – BRIN Public Relations. The National Research and Innovation Agency (BRIN) has several neutron scattering facilities, one of which is for Small Angle Neutron Scattering equipment. This facility is located in the Serpong Nuclear Area, used to conduct various researches, including in the field of Molecular Biology. Small angle neutron scattering is able to observe structural macromolecules in solution.
To introduce the benefits of this facility to researchers, lecturers, and students, BRIN through the Nuclear Energy Research Organization (ORTN) held a webinar on Small Angle Scattering (SAS) School under the theme “Structural and Biophysical Methods for Biological Macromolecules in Solution”. In the 5-day event starting Monday (07/03), the participants will get to know the use of the SAS method to study biological macromolecules in solution.
Acting Deputy for Science and Technology Human Resources, Edy Giri Rachman Putra in his welcome remarks said that it is important to conduct research on structural biology. “Why? Because we have a lot of opportunities and also adequate facilities to conduct structural biology research,” said Edy Giri.
Edy Giri also feels pleased and grateful for the presence of Dimitri Svergun from the European Molecular Biology laboratory (EMBL) as a resource person and the participation of younger generation who are struggling in the field of molecular biology. “I hope that one day our young generation, our young talents, can join doctoral or post-doctoral education at your place, in Hamburg, Germany,” said Edy Giri.
Edi hopes that the collaboration between BRIN and EMBL will continue to improve in the future, especially in term of education. “I believe that the cooperation between Indonesia and Germany will continue to improve in the future,” he continued.
On this occasion, Dimitri Svergun explained about the SAS technique and its use in biological macromolecular research. He gave an example that Biontech, a pfizer vaccine company, uses the SAS technique to examine RNA encapsulation so that it can be stable until it gets to the target cells in the body, and formation of antibodies can be successful. SAS is also used to examine the interaction between the spike protein of SARS Cov 2 virus and an inhibitor molecule so that it can inhibit viral infection to the body.
Meanwhile, a researcher at the Eijkman Center for Molecular Biology Research (PRBME), Sandi Sufiandi said that it is important to understand the science of structural biology in biomolecular research, especially because this science is closely related to translational medicine research which is currently developing.
“As we know, structural biology is an important science in translational medicine as well as in life science. The structure and structure shape will imply the function, so understanding the relationship between structure and function is very important for us to understand the mechanism, especially in biomolecular research,” said Sandi.
The event was also attended by other speakers from various foreign institutions, including Melissa Graewert (European Molecule Biology Laboratory), Jill Trewhella (University of Sydney), Al Kikhney (Xenocs), and Sandi Sufiandi from the Eijkman Center for Molecular Biology Research ( PRBME). (yrt,SET)